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Minnie has a cold. When we got her from the shelter they warned us that she might get an upper respiratory infection just from being in the shelter. About 2 weeks later she started sneezing and her "womanly" operation had to be cancelled. We took her to the vet and he gave her a shot of Amoxicillin and pills for 10 days. Right after that she started acting very weird - constant loud purring in short spurts with her mouth open, rubbing her paws on her face and something weird with her back end - kind of sticking it out. I thought for sure she was having a reaction to the antibiotic. She was just acting so strange. Then Paul said, "Maybe she's in heat." A quick Google look up and sure enough, Minnie was in heat. I guess with all the cats that we have had, we have never had one in heat. Izzy keeps looking at her like she is crazy. I hope this doesn't last too long!